
Ipecac Recordings has been one of my favorite record labels, if not my #1 top favorite, for almost a decade now.
Wiki Here
Here are my Top 15 Recommendations in no particular order (I like so much stuff on this label that I put a list of honorable mentions at the bottom that are worth your time as well):

1. Fantomas - The Director's Cut
see also: Delirium Cordia, Suspended Animation, Fantomas (self-titled)
2. Tomahawk - Mit Gas
see also: Tomahawk (self titled), Anonymous
3. Isis - Oceanic
4. Melvins/Lustmord - Pigs of the Roman Empire

5. Dalek - Absence
see also: From the Filthy Tongue of Gods and Griots
6. Mugison - Mugimama, Is This Monkey Music?
see also: Little Trip, Mugiboogie

7. Kaada - Music for Moviebikers
8. Hella - There's No 666 in Outer Space
9. Melvins - (a) Senile Animal
see also: Everything by the Melvins

10. Goon Moon - Licker's Last Leg
11. Zach Hill - Astrological Straits

12. Bohren & Der Club of Gore - Dolores
see also: Black Earth
13. Beak> - Beak>

14. Steroid Maximus - Ectopia
15. Phantomsmasher - Phantomasmasher
Stuff I didnt want to leave unmentioned (Honorable Mention, all high-quality releases):
Skeleton Key - Obtanium, Moistboyz - III, Ruins - Tzomborgha, Yoshimi and Yuka - Flower with No Color, Desert Sessions Vol. 9 & 10, Trevor Dunn's Trio Convulsant, Vincent and Mr. Green (self titled), General Patton vs. The Xecutioners (self titled), The Locust - Safety Second Body Last, Messer Chups - Crazy Price, Patton/Kaada - Romances CD and DVD, Farmer's Market - Surfin' USSR, Mike Patton - A Perfect Place and Mondo Cane, Zu - Carboniferous, Sax Ruins - Yawiquo
I guess they all can'tbe great though, so...
Don't Even Go Near These Albums:
Northern State - Can I Borrow This Pen?, Ghostigital - In Cod We Trust